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Sex, blood and parasites: how to block malaria transmission by the Anopheles mosquito

 

Many parasites utilize blood-feeding insects as vectors for transmission between human hosts. Our system of choice is the molecular interplay between Anopheles gambiae mosquitoes, the most effective malaria vectors in Africa, and Plasmodium falciparum parasites, the most dangerous agents of human malaria.
Our goal is to uncover the fundamental basis of how these two organisms interact, ensuring parasite transmission. In the long-term, our objective is to learn how to disrupt these processes and block malaria transmission in ways that are safe both to humans and to the environment.

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